Pesto Chicken Pasta Bake

Featured in: Oven-Cooked Favorites

This comforting pesto chicken pasta bake combines tender diced chicken, aromatic basil pesto, and gooey mozzarella in a satisfying one-dish meal. Simply cook your pasta al dente, sauté chicken with garlic and tomato sauce, then layer everything with cheese and bake until golden.

Ready in just 45 minutes with minimal prep, it serves 4 and works perfectly for weeknight dinners or casual entertaining. Customize with sun-dried tomatoes, roasted vegetables, or rotisserie chicken for quick variations.

Updated on Wed, 21 Jan 2026 16:50:00 GMT
A close-up of golden-baked Pesto Chicken Pasta Bake, with melted mozzarella and vibrant basil pesto sauce bubbling in a casserole dish. Save to Pinterest
A close-up of golden-baked Pesto Chicken Pasta Bake, with melted mozzarella and vibrant basil pesto sauce bubbling in a casserole dish. | spicykefta.com

The smell of bubbling cheese and basil always pulls me back to rainy Tuesday evenings when my roommate would whip up this exact dish after our late shifts. We would hover by the oven, watching the mozzarella turn golden and debating whether we could wait five whole minutes for it to rest. That first steamy forkful, with the way the pesto clung to every penne tube, became our definition of comfort food.

Last winter I made this for my sister during a particularly rough week at work. She took three bites, put her fork down, and just said this is exactly what I needed right now. Now whenever she texts that shes having a hard time, I show up with a baking dish covered in foil.

Ingredients

  • Penne or rigatoni (300 g): The ridges and tubes catch all that sauce perfectly, and I have learned that slightly undercooking the pasta is the secret to textural heaven
  • Chicken breasts (2 medium): Dicing them yourself gives you better control over portion sizes, though rotisserie chicken has saved my sanity more than once
  • Basil pesto (120 g): Homemade is lovely but a good quality jarred version works beautifully, just look for one without too much oil
  • Tomato passata or marinara sauce (300 ml): Passata gives you that smooth restaurant texture but chunky marinara adds nice body too
  • Garlic cloves (2): Freshly minced releases way more aroma than pre minced stuff, and that minute in the skillet makes all the difference
  • Olive oil (2 tbsp): This coats your chicken and helps the garlic bloom without burning
  • Shredded mozzarella (200 g): Low moisture cheese melts better and keeps your bake from becoming soupy
  • Grated Parmesan (30 g): The salty finish on top creates this gorgeous golden crust everyone will fight over
  • Salt and pepper: Season your chicken generously before cooking since the pasta will absorb some of that seasoning
  • Fresh basil leaves: Totally optional but that pop of green makes it look like you put way more effort in than you actually did

Instructions

Product image
Grill meats and vegetables indoors with beautiful sear marks and easy cleanup using minimal oil.
Check price on Amazon
Get your oven ready:
Preheat to 200°C (390°F) so you are not waiting around later when everything else is ready to go
Cook the pasta:
Boil those penne in salted water until just shy of al dente because they will finish cooking in the oven
Sauté the chicken:
Heat that olive oil and cook your seasoned chicken pieces until they are golden and cooked through, then add garlic for just one minute
Build the sauce:
Stir in half your pesto and all the tomato sauce, let it simmer for a couple minutes until everything gets friendly
Mix it all together:
Combine pasta, chicken sauce, remaining pesto, and half the mozzarella in your biggest bowl, folding gently
Assemble the bake:
Transfer everything to a greased baking dish and blanket it with the rest of the mozzarella and all that Parmesan
Bake to perfection:
Slide it into the oven for about 20 minutes until the cheese is bubbling and has those gorgeous brown spots
Practice patience:
Let it rest for five minutes so the sauce has time to set up, then scatter fresh basil on top if you are feeling fancy
Product image
Grill meats and vegetables indoors with beautiful sear marks and easy cleanup using minimal oil.
Check price on Amazon
A family-style serving of Pesto Chicken Pasta Bake, featuring tender chicken chunks and al dente penne coated in herby pesto and marinara. Save to Pinterest
A family-style serving of Pesto Chicken Pasta Bake, featuring tender chicken chunks and al dente penne coated in herby pesto and marinara. | spicykefta.com

My friend who claims to hate leftovers literally ate this cold from the container at midnight after a party. She texted me the next day asking for the recipe, completely shocked that the pasta was still perfectly textured after being refrigerated.

Making It Ahead

You can assemble everything up to a day in advance, cover it tightly, and keep it in the refrigerator. I have found that adding an extra five minutes to the baking time compensates for the cold start, and the flavors actually develop beautifully overnight.

Freezing Instructions

Wrap your assembled unbaked casserole in plastic then foil and it will freeze for up to three months. Thaw overnight in the refrigerator before baking, though honestly I have baked it from frozen by adding about twenty minutes and covering with foil for the first half.

Serving Suggestions

A crisp green salad with balsamic vinaigrette cuts through all that rich cheese perfectly. I also like putting out some crusty bread because people will want to mop up every last bit of sauce.

  • Pinot Grigio is the classic pairing but a chilled Chardonnay works beautifully too
  • Steamed broccoli or roasted asparagus on the side makes it feel like a complete meal
  • Leftovers reheat surprisingly well in the microwave, though the oven gives you back that crispy cheese top
Product image
Perfect for simmering soups, baking casseroles, and serving cozy one-pot meals straight from oven to table.
Check price on Amazon
Fresh basil garnish sits atop the bubbly Pesto Chicken Pasta Bake, revealing gooey mozzarella and golden Parmesan edges from the oven. Save to Pinterest
Fresh basil garnish sits atop the bubbly Pesto Chicken Pasta Bake, revealing gooey mozzarella and golden Parmesan edges from the oven. | spicykefta.com

This is the recipe I make when I want people to feel taken care of without spending my whole evening in the kitchen. Something about bubbling cheese and warm pasta just makes everything better.

Recipe FAQs

Can I use fresh pesto instead of store-bought?

Absolutely. Homemade pesto made with fresh basil, garlic, pine nuts, Parmesan, and olive oil works wonderfully and delivers superior flavor. Use the same quantity as store-bought pesto in this preparation.

What pasta shapes work best?

Penne and rigatoni are ideal because their tubes and ridges capture the pesto and sauce beautifully. Fusilli, farfalle, or any medium pasta shape that holds sauce well are also excellent choices.

How can I make this dish ahead?

Assemble the casserole completely in the baking dish, cover with plastic wrap, and refrigerate up to 24 hours. Add 5-10 minutes to baking time if cooking from cold. You can also freeze for up to 3 months before baking.

What are good wine pairings?

Crisp, dry white wines complement this dish beautifully. Pinot Grigio, Vermentino, or Sauvignon Blanc cut through the richness of the cheese and pesto while enhancing the fresh basil flavors.

Can I substitute the mozzarella?

While mozzarella is traditional for its mild flavor and melt quality, you can use ricotta, fontina, or a mix of cheeses. Avoid overly sharp varieties that might overpower the delicate pesto balance.

How do I know when the casserole is done baking?

The cheese should be melted and golden brown on top, and the sauce should be bubbling around the edges. A 20-minute bake at 200°C typically achieves this. If the top browns too quickly, tent with foil.

Pesto Chicken Pasta Bake

A golden, cheesy pasta casserole with tender chicken, vibrant basil pesto, and melted mozzarella baked to perfection.

Prep Time
15 minutes
Cook Time
30 minutes
Total Duration
45 minutes
Created by Chloe Patterson


Skill Level Easy

Cuisine Italian-American

Makes 4 Portions

Diet Details None specified

What You Need

Pasta

01 10.5 oz penne or rigatoni pasta

Chicken

01 2 medium chicken breasts (about 12 oz), diced

Pesto & Sauce

01 1/2 cup basil pesto, store-bought or homemade
02 1 1/4 cups tomato passata or marinara sauce
03 2 cloves garlic, minced
04 2 tablespoons olive oil

Cheese

01 2 cups shredded mozzarella cheese
02 1/4 cup grated Parmesan cheese

Seasoning

01 Salt and freshly ground black pepper to taste
02 Fresh basil leaves for garnish, optional

How To Make It

Step 01

Preheat oven: Set oven to 390°F and allow to reach full temperature.

Step 02

Cook pasta: Bring a large pot of salted water to boil. Add pasta and cook until just al dente. Drain and set aside.

Step 03

Sauté chicken: Heat olive oil in a large skillet over medium heat. Add diced chicken, season with salt and pepper, and cook for 5 to 7 minutes until cooked through and lightly golden.

Step 04

Build sauce: Add minced garlic to the skillet and cook for 1 minute. Stir in tomato passata and half of the pesto. Simmer for 2 to 3 minutes, then remove from heat.

Step 05

Combine ingredients: In a large mixing bowl, combine cooked pasta, chicken mixture, half of the mozzarella, and remaining pesto. Stir gently until evenly mixed.

Step 06

Assemble bake: Transfer mixture to a lightly greased baking dish. Top with remaining mozzarella and Parmesan cheese.

Step 07

Bake casserole: Place in preheated oven for 20 minutes, or until cheese is melted and golden and sauce is bubbling at edges.

Step 08

Rest and serve: Let rest for 5 minutes. Garnish with fresh basil leaves and serve immediately.

Tools You'll Need

  • Large pot
  • Colander
  • Skillet
  • Mixing bowl
  • Baking dish
  • Oven

Allergens

Review each ingredient for allergens and talk to your healthcare provider if you’re unsure.
  • Contains wheat from pasta
  • Contains milk from mozzarella, Parmesan, and pesto
  • May contain tree nuts if pesto contains pine nuts
  • Verify all ingredient labels for additional allergen information

Nutrition Info (per portion)

For informational purposes only; always seek medical advice for nutrition.
  • Calories: 610
  • Fats: 26 g
  • Carbohydrates: 55 g
  • Proteins: 38 g